Infant

Cell cycle networks link gene expression dysregulation, mutation, and brain maldevelopment in autistic toddlers

Genetic mechanisms underlying abnormal early neural development in toddlers with Autism Spectrum Disorder (ASD) remain uncertain due to the impossibility of direct brain gene expression measurement during critical periods of early development. Recent …

Different functional neural substrates for good and poor language outcome in autism

Autism (ASD) is vastly heterogeneous, particularly in early language development. While ASD language trajectories in the first years of life are highly unstable, by early childhood these trajectories stabilize and are predictive of longer-term …

Prediction of autism by translation and immune/inflammation coexpressed genes in toddlers from pediatric community practices

IMPORTANCE: The identification of genomic signatures that aid early identification of individuals at risk for autism spectrum disorder (ASD) in the toddler period remains a major challenge because of the genetic and phenotypic heterogeneity of the …