Preschool

Alexithymia in children with and without autism spectrum disorders

Alexithymia refers to pronounced difficulty in identifying and describing one's own emotions and is associated with an externally oriented focus of thinking. Alexithymia is known to be much more common in adults with autism spectrum disorders (ASD) …

Identification and validation of biomarkers for autism spectrum disorders

Cell cycle networks link gene expression dysregulation, mutation, and brain maldevelopment in autistic toddlers

Genetic mechanisms underlying abnormal early neural development in toddlers with Autism Spectrum Disorder (ASD) remain uncertain due to the impossibility of direct brain gene expression measurement during critical periods of early development. Recent …

Different functional neural substrates for good and poor language outcome in autism

Autism (ASD) is vastly heterogeneous, particularly in early language development. While ASD language trajectories in the first years of life are highly unstable, by early childhood these trajectories stabilize and are predictive of longer-term …

Prediction of autism by translation and immune/inflammation coexpressed genes in toddlers from pediatric community practices

IMPORTANCE: The identification of genomic signatures that aid early identification of individuals at risk for autism spectrum disorder (ASD) in the toddler period remains a major challenge because of the genetic and phenotypic heterogeneity of the …

A meta-analysis of sex differences in human brain structure

The prevalence, age of onset, and symptomatology of many neuropsychiatric conditions differ between males and females. To understand the causes and consequences of sex differences it is important to establish where they occur in the human brain. We …

Moral dilemmas film task: A study of spontaneous narratives by individuals with autism spectrum conditions

People with autism spectrum conditions (ASC) have difficulties with mentalizing, empathy, and narrative comprehension. A new test of social and narrative cognition, the Moral Dilemmas Film Task, was developed to probe individuals' spontaneous …